When using base editors to inactivate antibiotic resistance genes, it is useful to track how many resistant bacteria remain over multiple generations. This helps assess the stability of the edited population and understand how resistance levels change over time. By monitoring bacterial growth and resistance, researchers can evaluate the effectiveness of gene inactivation and any potential reversion events.

This app helps evaluate the distribution of residual antibiotic-resistant bacteria across successive generations. Cells that lose antibiotic resistance due to base editor-mediated gene inactivation become sensitive and are gradually eliminated from the population when exposed to antibiotics.